Outro is the first service for safe, evidence-based antidepressant tapering, designed by expert clinicians and patients who’ve been there.

The first evidence-based approach to stopping medications
Based in Dr. Mark Horowitz's leading research, Outro's tapering program combines neurobiology-based tapering, integrative approaches and virtual care to provide an accessible, personalized path off medication.


Science-based taper plans
A neurobiology-based method that's personalized to you, hyperbolic tapering helps minimize withdrawal symptoms and reduces the risk of relapse.

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Support from expert clinicians
Trained by world-leading experts in deprescribing, Outro's clinical team is equipped to help build your taper plan and support you with regular visits.


Replace medication with holistic health practices
Get expert support in building skills around nutrition, exercise, sleep hygiene and more—whatever you'd like to work on for your mental health.

Hyperbolic Tapering
The first tapering method based on neurobiology
Despite the millions of people prescribed antidepressants, there have been no evidence-based approaches to getting off them.
Outro's method is the first approach based on science, accounting for the non-linear effect of dose changes on the brain, and putting the patient at the center of the tapering process.
How it works
Start building your personalized taper plan today
Complete the onboarding
Answer a brief series of questions to see if you could be a fit for our virtual tapering program.
Attend your first visit
Meet with one of our clinicians who can assess your eligibility and build you a personalized taper plan.
Join our taper program
Become a member of Outro's tapering program and receive ongoing support on your path off medication.