Taper Management Program

Tapering tailored to you, based on science

Outro's tapering programs combine the first neuroscience-based methods with holistic non-drug support—all delivered by licensed clinicians, trained by world-leading experts.

Dr. Mark Horowitz | Hyperbolic Tapering

Developed by patients, clinicians and researchers from leading institutions

Taper Management Program

Combining safe tapering with non-drug mental wellness

Neurobiology-based tapering

Our clinical team develops an evidence-based, flexible tapering plan that's personalized to each patient—taking into account your medication history, health status and unique life situation.

Support from expert clinicians

With monthly appointments and ongoing messaging, your Outro care team stays with you every step of the way—from monitoring withdrawal symptoms to prescribing compounded medications.

Non-drug mental wellness

Build your skills in sustainable, non-drug mental wellness practices like mindfulness, nutrition, movement, sleep hygiene and more, through clinician support and our resources library.

Hyperbolic Tapering

A neuroscience-based method for reducing withdrawal

Developed by our co-founder Dr. Horowitz, hyperbolic tapering safely reduces medication dosage in a precise, step-by-step fashion—based on pharmacological principles. It serves as the backbone of Outro's tapering programs.

Based on the latest evidence

Our evidence-based methods are based on neurobiology, and designed to minimize withdrawal symptoms from antidepressants.

Grounded in neurobiology

Through personalized tapering plans and holistic education, Outro helps reduce your risk of depression or anxiety relapse.

Designed to reduce withdrawal

Sustainability is key, and that's why we provide a suite of holistic health resources around topics like mindfulness, nutrition and movement.

How It Works

Personalized tapering support, from start to finish

Complete the onboarding survey

Take a few minutes to set up your account, tell us about your antidepressant discontinuation goals, and choose a time to meet your clinician virtually.

Attend your first visit

Discuss your symptoms and health history in depth with a licensed clinician who is specially trained in safe deprescribing.

Receive your tapering plan

Your clinician will partner with you to build a tapering plan designed just for you. You can take it as fast or as slow as you need, and the custom doses will be mailed right to your door.

Taper with ongoing support

Share your progress and any concerns with your clinician during monthly visits. You can also message in between visits to ask questions and check in on how you’re feeling.

Learn More

Common questions

Explore commonly asked questions about Outro's services, medication withdrawal, tapering and more.

How does Outro help minimize my risk of withdrawal and relapse?

Outro provides flexible, medically-supervised tapering plan with gradual dose reductions tailored just for you. Our hyperbolic tapering method, where reductions become progressively smaller, gently minimizes nervous system disruption and withdrawal discomfort. We personalize your tapering plan based on your response, preferences, and what's happening in your life.

How is Outro different from working with another provider?

Safe antidepressant deprescribing requires a comprehensive approach that is often difficult for an individual prescriber to provide due to the time required. It also requires up-to-date knowledge on the latest techniques in tapering antidepressants that are not yet widely taught in the United States. Think of Outro as a specialist in tapering.

At Outro, we walk with you every step of the way. Our specialized, high-touch care team takes time to get to know you and your goals, and provides an advanced, individualized approach to tapering off antidepressants informed by the latest guidance and clinical evidence. Through Outro’s app, your symptoms and progress are continuously monitored by your provider, who can reach out to offer coping strategies or adapt your care plan accordingly. If you have questions or concerns that arise in between appointments, your Outro provider is available via 1-to-1 chat.

What if I've tried to stop before?

Many people have difficulties when they try to go off antidepressants. Our team of expertly trained clinicians will develop a tailored tapering program, informed by the latest scientific evidence and designed to minimize withdrawal effects - even for these people who have tried to stop before.

What medications does Outro taper?

We currently offer taper management for antidepressant medications (e.g., duloxetine, escitalopram, sertraline, venlafaxine). You can see the full list here.

We are making preparations to expand to other psychotropic medications like benzodiazepines and gabapentinoids, which also follow the hyperbolic tapering method. You can express an interest in tapering these medications in our sign-up form.

Available in several states and growing

Outro is now accepting patients in several states and actively expanding. If you don't see your state here, join the waitlist via the onboarding flow.