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Dr. Mark Horowitz's Method to Tapering Antidepressants – Available Now

Personalized antidepressant taper plans

Expert psychiatric clinicians

Start tapering in under 2 weeks

Holistic mental health support

Hyperbolic Tapering

Personalized antidepressant tapering, based on neuroscience

Outro founder Dr. Mark Horowitz developed the hyperbolic tapering method based on his research, and his own challenging experience stopping an SSRI he was on for 15 years.

Science-based tapering

A tapering program that cares, and works

85%

Tried stopping drugs like antidepressant before finding Outro's program

Most patients attempted to taper with their existing prescriber, but were unsuccessful.

9x

Better tapering experience compared to other providers

Patients have a far better experience with Outro (patient feedback surveys).

7x

Higher success than standard tapering protocols

Hyperbolic tapering has a significantly higher success rate (van Os, 2021).

Expert Clinicians

Clinicians who support you every step of the way

The relationship matters. Our clinicians are deeply experienced in antidepressant withdrawal and tapering, and stay with you from start to finish, adjusting the plan as your body responds.

One clinician, start to finish

You're paired with one clinician who knows your history and goals—no starting over each visit.

Tapering expertise

Our clinicians are trained in hyperbolic tapering by world-leading experts in tapering, like Dr. Mark Horowitz.

Symptoms guide the plan

Symptom reports shape every dose adjustment. If your body needs to slow down, we slow down.

We handle the prescription

Compounded doses at your door, refill coordination, and between-visit messaging—so you can focus on how you feel.

Reasons people taper their antidepressants with Outro

The safest way to taper, based on the latest science

With neuroscience, expert guidance and symptom tracking, Outro improves your odds of a safe and successful taper.

Lower exposure to several long-term medication risks

Limit your exposure to the long-term risks like weight gain, metabolic dysfunction, cognitive decline and, overall mortality.

Reduce the risk of depression relapse

Slow, hyperbolic tapering can reduce the risk of depression and anxiety relapse, which is often associated with withdrawal symptoms.

Work with clinicians trained in safe deprescribing

Outro's team of clinicians are trained by world-leading experts, to guide taper plans that are based on science and personalized to you.

Get custom dose sizes your doctor won't prescribe

We help you access smaller, compounded prescriptions to help you taper safely—something traditional care can’t match.

Build sustainable, drug-free mental health practices

We support you with tools and coaching around sleep, nutrition and more, to help you feel better without relying on medication.

Get back your full range of human emotions

As you progress off your drug, feel the healthy return of emotions that antidepressants keep muted—helping you live a fuller life.

Take back control of your mental health journey

Build skills to manage your mental health, that exist beyond the medication-focused system you're used to.
"When I first contacted the Outro team, I was met with compassion and understanding. For me, this is the ultimate missing piece in most traditional approach to tapering off antidepressants."
Lilly
Tapering Sertraline
"My primary care doctor told me to stop cold turkey and after 48 hours I was so uncomfortable I had to start taking the medication again and lost hope on being able to get off this drug until I found Outro."
Jennifer
Tapering Escitalopram
"With Outro, the tapering process is so much slower, allowing enough time between each dose to determine symptoms, and adjust the dosage if necessary. I feel safe and I feel heard."
Jonathan
Tapering Effexor

Want to explore your personalized antidepressant taper plan?

Speak with an Outro clinician to learn more about how we support you—each and every step of the way.