See if you're eligible
Online antidepressant tapering clinic

Hyperbolic tapering, with guided support

For SSRIs and SNRIs like Effexor, Lexapro and Zoloft. Start by meeting a tapering clinician to see if you're eligible.

  1. 1

    Answer a few questions online

  2. 2

    Meet a tapering clinician to see if you're eligible

  3. 3

    If you're eligible, start your taper

Free to sign up · $99 evaluation · HSA/FSA eligible
Example taper: typical vs hyperbolicA typical taper makes same-size cuts and drops from 25 mg to 0 in one step. A hyperbolic taper makes smaller cuts as the dose gets lower.Example taperTypical taperSame-size cuts050100Daily dose (mg)Time →25 mg to 0in one stepHyperbolic taperSmaller cuts as the dose gets lower050100Daily dose (mg)Time →Based on the Maudsley Deprescribing Guidelines.Illustrative. Your clinician sets your doses and pace.
How it works

Getting started is simple

Three steps. You only continue if it's right for you.

01

Answer a few questions

About your medication and past attempts, online.

02

Meet a tapering clinician

A $99 video visit to see if you're eligible.

03

Start your taper

If you're eligible: a personalized plan, custom doses and ongoing support.

What is hyperbolic tapering?

At higher doses, cutting a few milligrams changes the drug's effect only a little. At lower doses, the same few milligrams changes it a lot, which is why the last part of a taper is often the hardest. Hyperbolic tapering makes each cut smaller as the dose gets lower, so each step feels more even.

Hyperbolic tapering plans
Clinicians trained in deprescribing
Holistic non-drug support

Why hyperbolic tapering is hard to do alone

Clinician pointing to a hyperbolic taper curve of gradual antidepressant dose reductions
The doses don't exist off the shelf

Late-stage steps can be fractions of a milligram. Most tablets can't be split that small. Compounded liquids and capsules can.

Karen LaFlair, psychiatric nurse practitioner at Outro Health, specializing in antidepressant tapering
The pace has to move with you

A good schedule slows down, holds or pauses based on how you feel. Your clinician adjusts it with you.

Hand pouring antidepressant capsules from a prescription bottle
Withdrawal can look like relapse

A clinician trained in tapering can help tell the difference, so a rough patch doesn't send you back to a higher dose.

Two women smiling together over a phone, supporting each other
Looking for a schedule or calculator?

Your schedule depends on your medication, dose and history. Ours are built by a clinician, not a calculator.

Real stories

Hyperbolic tapering, from people doing it

Members tapering with custom doses and a clinician by their side.

No one tells you that stopping these drugs is a trip through hell that can damage many aspects of your life. The only way to survive (in my opinion) is with the help of experts and others who have undertaken this journey before you. You will need a guide and someone to hold your hand - Outro is that guide.
Illustrated portrait of Sandi, an Outro Health patient tapering venlafaxine
Sandi

Tapering Venlafaxine

I thought I may be on these meds forever I can at least now see the light at the end of the tunnel and will get to meet myself after all these years and learn what Lily likes.
Illustrated portrait of Lily, an Outro Health patient tapering sertraline
Lily

Tapering Sertraline

Just knowing I'm not alone has been the biggest comfort to me. Outro's clinicians have been nothing short of compassionate and they actually listen closely to you and believe you when you say 'hey, this is what I'm feeling.' I would never do this without this kind of support again.
Illustrated portrait of Kelly, an Outro Health patient tapering venlafaxine
Kelly

Tapering Venlafaxine

When I started researching going off of SSRIs after extended use (I've been on 200mg for 14 years) I was alarmed to learn that withdrawal can be worse than the original symptoms. Having a place like Outro, that specializes in tapering off safely with minimal pain, is such a relief.
Illustrated portrait of Jennifer, an Outro Health patient tapering sertraline
Jennifer

Tapering Sertraline

A way to get hyperbolic tapering help from a real professional. This doesn't exist anywhere and leaves many of us whose minds and bodies have become dependent on these drugs some hope of getting off of them.
Illustrated portrait of James, an Outro Health patient tapering citalopram
James

Tapering Citalopram

I know it's scary, especially after so many years and even decades. But Outro works so closely with you and accommodates your needs while also making sense of it to you. I may be wording this bad but I really mean it when I say Outro has changed my life and what I thought possible for myself.
Illustrated portrait of Brooke, an Outro Health patient tapering fluoxetine
Brooke

Tapering Fluoxetine

Start with a $99 evaluation

A 45-minute video visit to see if you're eligible. If you continue, membership is $225/month and includes:

Personalized hyperbolic taper plan

Monthly video visits with your clinician

Messaging between visits

Access to custom compounded prescriptions

Peer support and lifestyle classes

Pay with your HSA or FSA card

Neuroscience-Based Tapering

Hyperbolic tapering, with a clinician who gets it

9/10 patients have tried to get off their antidepressant before finding Outro Health

93% of patients trust Outro Health clinicians with their taper more than their previous prescriber

7x: hyperbolic tapering has a significantly higher stopping success rate than standard protocols

95% of patients had a better experience tapering with Outro Health

Dr. Mark Horowitz

World-leading experts in safe deprescribing

If your last taper attempts didn't work, it probably wasn't your fault. 9/10 long-term antidepressant users experience withdrawal symptoms, which make stopping difficult. We use the first science-based method to limit withdrawal symptoms.

Outro Health's Approach

Not your average tapering experience

Most psychiatric care is built around starting medications. We built Outro Health around stopping them.

Standard care
Linear pill-strength reductions

Cuts using whatever tablet sizes the pharmacy stocks leading to withdrawal symptoms.

Hyperbolic tapering

Dose reductions aligned to neurobiology, per the Maudsley Deprescribing Guidelines.

Generic medication sizes

Most prescribers don't write for compounded medications. You taper using whatever the manufacturer makes.

Custom prescriptions

Liquid and capsule formulations let us calibrate each step to a fraction of a milligram.

Clinicians who add medication

Psychiatric training covers starting medications, with little formal instruction on stopping them.

Clinicians who remove medication

Clinicians who specialize in coming off psychiatric medications, grounded in the deprescribing literature.

Misdiagnoses withdrawal

Symptoms often misread as the original condition returning, leading to re-prescription, higher doses, or more medications.

Manages withdrawal

We distinguish withdrawal from relapse, adjust the pace, and keep moving forward instead of backward.

Pace set by the calendar

Reductions happen on appointment cadence, often faster than the nervous system can adjust.

Pace set by your nervous system

We slow down, hold steady, or pause whenever your body needs us to—without restarting from zero.

Wait for the next visit

Symptoms between appointments wait for the next 15-minute slot, sometimes weeks away.

Between-visit support

Care team messaging plus regular check-ins throughout your taper—not just at appointments.

FAQs

Questions about hyperbolic tapering and how Outro does it.

How does Outro Health help reduce my risk of withdrawal and relapse?

Outro Health provides flexible, medically-supervised tapering plan with gradual dose reductions tailored just for you. Our hyperbolic tapering method, where reductions become progressively smaller, gently minimizes nervous system disruption and withdrawal discomfort. We personalize your tapering plan based on your response, preferences, and what's happening in your life.

How is Outro Health different from working with another provider?

Safe antidepressant deprescribing requires a comprehensive approach that is often difficult for an individual prescriber to provide due to the time required. It also requires up-to-date knowledge on the latest techniques in tapering antidepressants that are not yet widely taught in the United States. Think of Outro Health as a specialist in tapering.

At Outro Health, we walk with you every step of the way. Our specialized, high-touch care team takes time to get to know you and your goals, and provides an advanced, individualized approach to tapering off antidepressants informed by the latest guidance and clinical evidence. Through Outro Health’s app, your symptoms and progress are continuously monitored by your provider, who can reach out to offer coping strategies or adapt your care plan accordingly. If you have questions or concerns that arise in between appointments, your Outro Health provider is available via 1-to-1 chat.

What is hyperbolic tapering?

Hyperbolic tapering (sometimes called the Horowitz-Taylor method) is based on the fact that as antidepressant dose goes up, drug action on brain cells increases, but not in equal steps. Higher dosages have less and less additional influence – a decreasing return on investment. The graph showing this is called a hyperbolic curve (goes up faster at low doses, and flatter at higher doses).

Tapering based on this method gradually reduces the drug following this natural curve, with the size of dose reduction getting smaller as the dosage gets closer to 0mg. These very low doses are difficult to make up with commonly available tablets, so compounded medications become important. To learn more, speak with an Outro Health clinician by scheduling your evaluation.

What if I've tried to stop before?

Many people have difficulties when they try to go off antidepressants. Our team of expertly trained clinicians will develop a tailored tapering program, informed by the latest scientific evidence and designed to minimize withdrawal effects - even for these people who have tried to stop before.

What medications does Outro taper?

We currently offer taper management for antidepressant medications. You can see the full list here.

We are making preparations to expand to other psychotropic medications like benzodiazepines, which also follow the hyperbolic tapering method.

See if hyperbolic tapering is right for you

Answer a few questions online, then meet a clinician trained in hyperbolic tapering.

Woman lifting her dog outdoors under a clear blue sky
See if you're eligible